American Gut
$1,286,382 raised
8471 contributors
3 Years running
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World's largest open-source science project to understand the microbial diversity of the Human Gut. Learn which microbes live in your gut, skin & mouth. Join over 10,000 people, get a home sampling kit and support the research. More ...

**Please note that UCSD will be closed for the holidays from December 24th, 2016 to January 3rd, 2017. If you are sending in a sample, please ensure that it arrives before December 24th, or wait until after the holidays. Orders made during this time period will be sent out after UCSD re-opens. Thank you!

The Human Microbiome Project and other microbiome projects worldwide have laid an important foundation for understanding the trillions of microbes that inhabit our bodies and their impact on health and disease. However, opportunities for the public to get involved in such research have been limited. Now, American Gut gives you an opportunity to join this research project and learn what’s living on and inside you.

American Gut is a project built on open-source, open-access principles. The data we collect is de-identified and then deposited into open repositories for the benefit of other researchers and scientists.

Join the project!

Joining is simple! Select the kit you would like from the list of options on the left-hand side by clicking “Claim this perk”. Your kit will be sent via mail within 1-2 weeks after payment.

International participants are also welcome to join. However, please note that a $25 shipping fee does apply. We ask that samples be sent back to our lab within 48-72 hours. The cost of expedited shipping to our lab in the US from some locations can be expensive, so it is also recommended that you look into the cost of return shipping.

If you are currently residing in Europe, visit our sister site the British Gut to join this research project.

A few important points to remember before joining this research project:

1. Note your de-identified information will be part of a research study and will be made available in a publicly available research database. That is, any personal information that might easily identify who you are will be removed before being placed in the public database.

2. If you decide that you no longer wish to continue in this study, you will be requested to contact the American Gut Project help line (info@americangut.org) to inform us of your intent to withdraw. You may request a refund within 50 days of your original payment if you have not yet used your kit. Please note that the Fundrazr transaction fee will be deducted from your refund.

3. The consent forms are maintained on the participant website; details are included in your kit. To sign the consent form, you must agree to use an electronic format for your signature in accordance with the United States' eSIGN Act and California's UETA Act. You have the right to obtain the electronic record in a non-electronic form.

4. The results you receive from submitting a sample are not meant to act as medical or health diagnoses. We will not be able to provide any clinical or medical information from your results.

You may find a full overview of the project at http://humanfoodproject.com/americangut/, or visit us at www.americangut.org.

 

 

 

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Perks

$99
Find Out Who’s In Your Gut
  • 4597 claimed
The ribosome is the factory that makes proteins and is found in all cells, and fascinatingly it is mostly made of RNA. One RNA subunit, called the 16S rRNA, is especially effective as a barcode for understanding which microbes (specifically, bacteria and archaea) are found in a given sample. This PERK includes DNA extraction and 16S rRNA sequencing of one stool sample (or an oral or skin sample – the same kit works for any of these), and shows which bacteria and archaea were present in that sample along with how much of each kind. You be able to view, download and print a high-resolution certificate suitable for framing of your results and access to more detailed taxa report of your results - which can be viewed online and downloaded into Excel.
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$6.45
USPS Priority Mail Shipping
  • 454 claimed
Get your kits faster with two day USPS Priority Shipping by adding this perk to your order. Only valid for US orders.
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$17
American Gut T-Shirt
  • 0 claimed
Show your support for microbiome research with these quirky (and really awesome) American Gut t-shirts! These limited quantity shirts (made of 100% polyester) will be available through December 22nd. Priority USPS shipping is included with all U.S. orders.

Please email your shirt size to info@americangut.org. Available sizes are S through XL.
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$75
ASD-Cohort Parent
  • 82 claimed
This Perk is for the parent of a participant enrolled in American Gut's "ASD-Cohort." Note the Perk is for ONE swab/kit. If both parents want to enroll, multiple by 2. The reduced Perk rate is made possible by a generous grant. If you have an ASD child and want to have them considered for a FREE gut microbiota analysis, please email info@americangut.org
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$129
You Plus The World
  • 436 claimed
This is two kits: 1 for you and one for someone from either Africa, South America or Asia. Your support of this PERK will allow us to sequence more people from around the world as part of our ongoing research. DNA extraction and 16S rRNA sequencing of one stool sample (or an oral or skin sample - the same kit works for any of these).
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$180
Microbes For Two: See What You’re Sharing
  • 1643 claimed
DNA extraction and 16S rRNA sequencing of two stool samples, e.g. couples, father/son, mother/daughter, you and your dog (or, one stool and say an oral sample – is up to you – mix and match how you like). You be able to view, download and print a high-resolution certificate suitable for framing of your results and access to more detailed taxa report of your results - which can be viewed online and downloaded into Excel.
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$260
Microbes For Three
  • 370 claimed
DNA extraction and 16S rRNA sequencing of three stool samples if there are three of you in your home (or, two stools and say an oral sample or one stool, one oral and one skin – is up to you – mix and match how you like). You be able to view, download and print a high-resolution certificate suitable for framing of your results and access to more detailed taxa report of your results - which can be viewed online and downloaded into Excel.
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$320
Microbes For Four
  • 365 claimed
DNA extraction and 16S rRNA sequencing of four stool samples if there are four of you in your home (or, two stools and say two oral samples or two stools and one oral and one skin). It’s up to you – mix and match, you get the idea. You be able to view, download and print a high-resolution certificate suitable for framing of your results and access to more detailed taxa report of your results - which can be viewed online and downloaded into Excel.
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$500
A Week Of Feces
  • 28 claimed
(you heard us!) DNA extraction and 16S rRNA sequencing of up to 7 samples. Collect a stool sample every day of the week and send to us along with your detailed dietary information etc. See how your New Year’s resolution changed your gut microbes! Or see how much those antibiotics you took for a sniffle affected you. Or your travel to Mexico, where you drank the water. Our microbes change a lot over our lives, but what affects them the most remains largely a mystery.
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$1,500
All In The Family
  • 7 claimed
Shallow shotgun metagenomic analysis of up to four fecal samples (furry family members also ok), including mapping to reference genomes and comparing profiles of genetic similarities and differences among different family members. Shallow shotgun metagenomics means instead of using the 16S rRNA as a marker gene, we fragment all the DNA in the sample, grind it up, sequence it in small pieces, and try to figure out what it is afterwards. The bad news is that much of this information is still mysterious because we don’t know the complete genomes of most of the microbes in there, but the good news is that you can get an insight into the gene functions, not just which microbes are there.
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$2,500
Beyond Bacteria
  • 18 claimed
Deeper shotgun metagenome and virome characterization of one sample, plus additional marker gene sequencing (16S rRNA, 18S rRNA and ITS, for you sequencing wonks) to characterize not just the bacteria but also the viruses, microbial eukaryotes (like giardia), and fungi in your gut. This PERK allows you to see everything, not just the bacteria, that’s in there. 18S rRNA is similar to 16S rRNA but for eukaryotes (like us); ITS is the internally transcribed spacer, a very fast-evolving region that lets you see very detailed information about the species that are there.
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$3,750
Functional Feces
  • 3 claimed
Deeper shotgun metagenomic characterization of up to 7 stool samples, providing an analysis of the variability of functions over time. This could be a great opportunity to see if fasting or extreme diet has an effect on your microbes! We would recommend doing this as a timeseries, either daily, weekly or monthly, to track how you’re doing when you travel or when you change your diet (those New Year’s resolutions again!)
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$5,000
A Genome From Your Gut
  • 0 claimed
Deep characterization of a single stool sample by shotgun metagenomics, includes best-effort attempt to assemble one or more bacterial genomes out of your gut. You will get a framed poster of the assembled genome showing differences to its close relatives. Only serious need inquire – please email info@amergicangut.org to express your interest before signing up for this one.
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$15,000
What Are They Actually Doing
  • 1 claimed
RNA expression profiling of up to five samples, which tells you not only who is in your gut but what genes they have turned on. Ideal for seeing responses to probiotic yogurt or other short-term dietary changes! RNA, or ribonucleic acid, is primarily used as the messenger in the cell transmitting DNA to protein: looking at the RNA therefore tells you which genes are switched on, which often happens at much faster time scales than change in the genes or species that are in your gut but can have huge functional consequences in terms of producing metabolites that could affect health. Only serious need inquire – please email info@amergicangut.org to express your interest before signing up for this one.
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$25,000
Hundreds Of Genomes From Your Gut
  • 0 claimed
Be among the first in the world to get the most detailed map of your gut microbiome and help us push the state-of-the-art in high-throughput sequence technology of microbial communities. We will perform ultra-deep sequencing of your microbiome sample aimed at generating as many individual bacterial genomes as possible (we can’t tell you how because the details of the technique are still under wraps prior to publication). Only serious need inquire – please email info@amergicangut.org to express your interest before signing up for this one.
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